Well, I'm from Alabama, not Louisiana, and Louisiana is kind of its own thing. But the guy who plays Rene sounds fantastic to me--I love trying to transcribe his lines phonetically. And I was shocked to find out that Ryan Kwanten is--what, Australian? Like, that genuinely blew my mind. Sam Trammell is pretty good (he may have grown up in the South? I read something somewhere?), although "chere" sounded really weird in the first couple of episodes to me. There may be no convincing way to say it if you're not actually Cajun. Stephen Moyer's is reasonably good--he has moments where he sounds like he's trying way too hard (SUCKY IS MAHN), although maybe he's trying to do an Old South/Civil War-era kind of thing. He's settled into it a bit better as the season's gone on. Anna Paquin's gets a little annoying, but I'm starting to think it's not that it's a bad Southern accent as it is just Sookie being annoying now and then. Rutina Wesley is--well, she's consistent, whatever it is she's doing. There's a point where you stop hearing the accent as something the actor's doing wrong or right and just as the way the character talks. Like "Sookie's annoying sometimes" or "Bill is old-fashioned and really earnest" or "Tara is sassy."